Nome |
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alpha-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication, file dd8a4bf7-e251-20a0-e053-d805fe0a8cb0
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259
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Astrocytes-derived extracellular vesicles in motion at the neuron surface: Involvement of the prion protein, file dd8a4bf9-0c1d-20a0-e053-d805fe0a8cb0
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173
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In Vitro Aggregation Assays for the Characterization of α-synuclein Prion-Like Properties, file dd8a4bf7-1def-20a0-e053-d805fe0a8cb0
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132
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Mycobacterium tuberculosis chaperonin 10 forms stable tetrameric and heptameric structures. Implications for its diverse biological activities, file dd8a4bf7-1e8c-20a0-e053-d805fe0a8cb0
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127
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alpha-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication, file dd8a4bf7-e250-20a0-e053-d805fe0a8cb0
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119
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Structural Consequences of Copper Binding to the Prion Protein, file dd8a4bf8-d559-20a0-e053-d805fe0a8cb0
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107
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Characterization of prion protein function by focal neurite stimulation, file dd8a4bf7-267e-20a0-e053-d805fe0a8cb0
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101
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NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features, file dd8a4bf7-0ff5-20a0-e053-d805fe0a8cb0
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84
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On the role of the cellular prion protein in the uptake and signaling of pathological aggregates in neurodegenerative diseases, file dd8a4bf8-e0d1-20a0-e053-d805fe0a8cb0
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80
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The Priority position paper: Protecting Europe's food chain from prions, file dd8a4bf7-2237-20a0-e053-d805fe0a8cb0
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77
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Whole blood gene expression profiling in preclinical and clinical cattle infected with atypical bovine spongiform encephalopathy, file dd8a4bf7-267f-20a0-e053-d805fe0a8cb0
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62
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Molecular pathogenesis of prion diseases, file dd8a4bf7-80d3-20a0-e053-d805fe0a8cb0
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61
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The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein, file dd8a4bf7-e893-20a0-e053-d805fe0a8cb0
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59
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The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion, file dd8a4bf8-3a14-20a0-e053-d805fe0a8cb0
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58
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The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain, file dd8a4bf8-33b7-20a0-e053-d805fe0a8cb0
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57
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Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations, file dd8a4bf7-e71f-20a0-e053-d805fe0a8cb0
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54
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Small-Molecule Theranostic Probes: A Promising Future in Neurodegenerative Diseases, file dd8a4bf7-1d90-20a0-e053-d805fe0a8cb0
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53
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Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy, file dd8a4bf8-e066-20a0-e053-d805fe0a8cb0
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53
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Probing Early Misfolding Events in Prion Protein Mutants by NMR Spectroscopy, file dd8a4bf7-1d8f-20a0-e053-d805fe0a8cb0
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45
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Hemoglobin mRNA changes in the frontal cortex of patients with neurodegenerative diseases, file dd8a4bf7-e7f6-20a0-e053-d805fe0a8cb0
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45
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Defined α-synuclein prion-like molecular assemblies spreading in cell culture, file dd8a4bf7-1e0e-20a0-e053-d805fe0a8cb0
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44
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Elucidating the function of the prion protein, file dd8a4bf7-eb0c-20a0-e053-d805fe0a8cb0
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44
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Synthetic prions with novel strain-specified properties, file dd8a4bf7-1455-20a0-e053-d805fe0a8cb0
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43
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Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure, file dd8a4bf8-a506-20a0-e053-d805fe0a8cb0
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43
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The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion, file dd8a4bf7-1773-20a0-e053-d805fe0a8cb0
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40
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Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques, file dd8a4bf7-176d-20a0-e053-d805fe0a8cb0
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36
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Pin1 and neurodegeneration: a new player for prion disorders?, file dd8a4bf8-3085-20a0-e053-d805fe0a8cb0
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35
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Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation, file dd8a4bf7-1be8-20a0-e053-d805fe0a8cb0
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34
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Soil humic substances hinder the propagation of prions, file dd8a4bf8-2dcc-20a0-e053-d805fe0a8cb0
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34
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In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution, file dd8a4bf7-1451-20a0-e053-d805fe0a8cb0
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33
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Effect of extracellular vesicles derived from distinct brain cells on A beta toxicity and assembly: focus on microglia derived vesicles, file dd8a4bf7-e07f-20a0-e053-d805fe0a8cb0
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33
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A novel expression system for production of soluble prion proteins in E.coli, file dd8a4bf8-3146-20a0-e053-d805fe0a8cb0
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33
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Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids, file dd8a4bf8-db11-20a0-e053-d805fe0a8cb0
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33
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The alpha-synuclein RT-QuIC products generated by the olfactory mucosa of patients with parkinson’s disease and multiple system atrophy induce inflammatory responses in SH-SY5Y cells, file dd8a4bf9-0c1e-20a0-e053-d805fe0a8cb0
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33
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Modulation of alpha-synuclein aggregation by dopamine analogs, file dd8a4bf7-1cfd-20a0-e053-d805fe0a8cb0
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31
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Prion protein interaction with soil humic substances: environmental implications, file dd8a4bf7-26ec-20a0-e053-d805fe0a8cb0
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31
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Prion and prion-like protein strains: Deciphering the molecular basis of heterogeneity in neurodegeneration, file dd8a4bf8-d47a-20a0-e053-d805fe0a8cb0
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31
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New insights into structural determinants of prion protein folding and stability, file dd8a4bf7-20a2-20a0-e053-d805fe0a8cb0
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29
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Prion protein-specific antibodies-development, modes of action and therapeutics application, file dd8a4bf7-176f-20a0-e053-d805fe0a8cb0
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28
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Unique Structural Features of Mule Deer Prion Protein Provide Insights into Chronic Wasting Disease, file dd8a4bf8-d7e8-20a0-e053-d805fe0a8cb0
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27
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Prion protein paralog doppel protein interacts with alpha-2-macroglobulin: a plausible mechanism for doppel-mediated neurodegeneration, file dd8a4bf7-1d1f-20a0-e053-d805fe0a8cb0
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26
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Differential overexpression of SERPINA3 in human prion diseases, file dd8a4bf7-e9bc-20a0-e053-d805fe0a8cb0
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26
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Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia, file dd8a4bf7-e9f0-20a0-e053-d805fe0a8cb0
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26
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Hemoglobin mRNA changes in the frontal cortex of patients with neurodegenerative diseases, file dd8a4bf8-19e2-20a0-e053-d805fe0a8cb0
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26
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Pmca-generated prions from the olfactory mucosa of patients with fatal familial insomnia cause prion disease in mice, file dd8a4bf9-0a27-20a0-e053-d805fe0a8cb0
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26
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Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells, file dd8a4bf7-294b-20a0-e053-d805fe0a8cb0
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25
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Prion protein and aging, file dd8a4bf7-19fe-20a0-e053-d805fe0a8cb0
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24
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Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c), file dd8a4bf7-1dea-20a0-e053-d805fe0a8cb0
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24
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PrPC Controls via Protein Kinase A the Direction of Synaptic Plasticity in the Immature Hippocampus, file dd8a4bf7-77b4-20a0-e053-d805fe0a8cb0
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24
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Early structural features in mammalian prion conformation conversion, file dd8a4bf7-108e-20a0-e053-d805fe0a8cb0
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23
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De novo prions, file dd8a4bf7-16a8-20a0-e053-d805fe0a8cb0
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23
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Investigating the conformational stability of prion strains through a kinetic replication model, file dd8a4bf7-1d22-20a0-e053-d805fe0a8cb0
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23
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Differential overexpression of SERPINA3 in human prion diseases, file dd8a4bf7-e905-20a0-e053-d805fe0a8cb0
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23
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α-Synuclein RT-QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies, file dd8a4bf8-dfbc-20a0-e053-d805fe0a8cb0
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23
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Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia, file dd8a4bf7-e2cc-20a0-e053-d805fe0a8cb0
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21
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Involvement of PrPC in kainate-induced excitotoxicity in several mouse strains, file dd8a4bf8-3c36-20a0-e053-d805fe0a8cb0
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21
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Cytosolic prion protein in neurons, file dd8a4bf7-1c85-20a0-e053-d805fe0a8cb0
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20
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Profiling dopamine-induced oxidized proteoforms of β-synuclein by top-down mass spectrometry, file dd8a4bf9-0a12-20a0-e053-d805fe0a8cb0
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20
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Protease-sensitive synthetic prions, file dd8a4bf7-1128-20a0-e053-d805fe0a8cb0
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19
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Prion Protein Accumulation In Lipid Rafts of Mouse Aging Brain, file dd8a4bf7-1ded-20a0-e053-d805fe0a8cb0
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19
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Involvement of PrPC in kainate-induced excitotoxicity in several mouse strains, file dd8a4bf7-26ed-20a0-e053-d805fe0a8cb0
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19
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Progress towards structural understanding of infectious sheep PrP-amyloid, file dd8a4bf7-1bea-20a0-e053-d805fe0a8cb0
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18
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The cellular prion protein increases the uptake and toxicity of tdp-43 fibrils, file dd8a4bf9-0cee-20a0-e053-d805fe0a8cb0
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18
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Pharmacokinetics of quinacrine in the treatment of prion disease, file dd8a4bf8-249f-20a0-e053-d805fe0a8cb0
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16
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Mapping the prion protein distribution in marsupials: insights from comparing opossum with mouse CNS, file dd8a4bf8-35bb-20a0-e053-d805fe0a8cb0
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16
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Continuous quinacrine treatment results in the formation of drug-resistant prions, file dd8a4bf7-1595-20a0-e053-d805fe0a8cb0
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15
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Depicting conformational ensembles of α-synuclein by single molecule force spectroscopy and native mass spectroscopy, file dd8a4bf8-d7e7-20a0-e053-d805fe0a8cb0
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14
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Chronic α-synuclein accumulation in rat hippocampus induces lewy bodies formation and specific cognitive impairments, file dd8a4bf9-03ca-20a0-e053-d805fe0a8cb0
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11
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De novo mammalian prion synthesis, file dd8a4bf7-0f7c-20a0-e053-d805fe0a8cb0
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3
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Structural rearrangements at physiological pH: Nuclear magnetic resonance insights from the V210I human prion protein mutant, file dd8a4bf7-1559-20a0-e053-d805fe0a8cb0
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3
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Expression and activity of pre-dianthin 30 and dianthin 30, file dd8a4bf7-26fe-20a0-e053-d805fe0a8cb0
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3
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Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site, file dd8a4bf7-ac60-20a0-e053-d805fe0a8cb0
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3
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Hybrid lipoic acid derivatives to attack prion disease on multiple fronts, file dd8a4bf7-108b-20a0-e053-d805fe0a8cb0
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2
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Structural insights into alternate aggregated prion protein forms, file dd8a4bf7-10c1-20a0-e053-d805fe0a8cb0
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2
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A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers, file dd8a4bf7-1453-20a0-e053-d805fe0a8cb0
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2
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Cooperative binding of dominant-negative prion protein to kringle domains, file dd8a4bf7-158b-20a0-e053-d805fe0a8cb0
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2
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Copper coordination in the full-length, recombinant prion protein, file dd8a4bf7-1617-20a0-e053-d805fe0a8cb0
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2
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Structural determinants in prion protein folding and stability, file dd8a4bf7-1771-20a0-e053-d805fe0a8cb0
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2
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Modulation of Prion by Small Molecules: From Monovalent to Bivalent and Multivalent Ligands, file dd8a4bf7-1903-20a0-e053-d805fe0a8cb0
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2
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Gene expression profiling and therapeutic interventions in neurodegenerative diseases: a comprehensive study on potentiality and limits, file dd8a4bf7-190d-20a0-e053-d805fe0a8cb0
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2
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Rational approach to an antiprion compound with a multiple mechanism of action, file dd8a4bf7-19fa-20a0-e053-d805fe0a8cb0
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2
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Synthetic prions and other human neurodegenerative proteinopathies, file dd8a4bf7-1a00-20a0-e053-d805fe0a8cb0
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2
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Thioaptamer interactions with prion proteins: sequence-specific and non-specific binding sites, file dd8a4bf7-1a9d-20a0-e053-d805fe0a8cb0
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2
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Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice, file dd8a4bf7-1c84-20a0-e053-d805fe0a8cb0
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2
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Discovery of a class of diketopiperazines as antiprion compounds, file dd8a4bf7-1d02-20a0-e053-d805fe0a8cb0
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2
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Evidence for GroES acting as a transcriptional regulator, file dd8a4bf7-1e8b-20a0-e053-d805fe0a8cb0
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2
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Differential inhibition of prion propagation by enantiomers of quinacrine, file dd8a4bf7-1f97-20a0-e053-d805fe0a8cb0
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2
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Cochaperonins are histone-binding proteins, file dd8a4bf7-1fa8-20a0-e053-d805fe0a8cb0
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2
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Purificazione di proteine di mammifero in biotecnologia, file dd8a4bf7-1fac-20a0-e053-d805fe0a8cb0
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2
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Humic substances interfere with detection of pathogenic prion protein, file dd8a4bf7-209d-20a0-e053-d805fe0a8cb0
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2
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Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein, file dd8a4bf7-213f-20a0-e053-d805fe0a8cb0
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2
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Human prions and plasma lipoproteins, file dd8a4bf7-218e-20a0-e053-d805fe0a8cb0
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2
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Synthetic mammalian prions, file dd8a4bf7-21a3-20a0-e053-d805fe0a8cb0
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2
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Structural Studies of Prion Proteins and Prions, file dd8a4bf7-236c-20a0-e053-d805fe0a8cb0
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2
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Role of prion disease-linked mutations in the intrinsically disordered N-terminal domain of the prion protein, file dd8a4bf7-2685-20a0-e053-d805fe0a8cb0
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2
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The peculiar nature of unfolding of the human prion protein, file dd8a4bf7-0f8a-20a0-e053-d805fe0a8cb0
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1
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Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes, file dd8a4bf7-10b3-20a0-e053-d805fe0a8cb0
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1
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Gene expression profiling to identify druggable targets in prion diseases, file dd8a4bf7-11a2-20a0-e053-d805fe0a8cb0
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1
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Oxidation of methionine residues in the prion protein by hydrogen peroxide, file dd8a4bf7-11f2-20a0-e053-d805fe0a8cb0
|
1
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Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc?, file dd8a4bf7-12d6-20a0-e053-d805fe0a8cb0
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1
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Totale |
3.153 |